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NextBioForm at RISE
Description
Interested in advancing biologically based pharmaceuticals?
NextBioForm, coordinated by RISE together with 18 partners, provides cutting-edge research on formulation and characterisation of biobased drug products.
Neutron and photon techniques offer unique advantages in life science. They enable studies ranging from protein structures to molecular dynamics in complex biological systems—at resolutions not accessible with other methods.
Biological systems, rich in water and hydrogen, are particularly well suited for neutron-based analysis. By leveraging the sensitivity of neutrons to hydrogen and deuterium, these methods provide valuable insights into structure and dynamics.
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NextBioForm is a competence centre, coordinated by RISE, with 18 partners, providing cutting-edge research on industrially relevant issues for the formulation and characterisation of biologically based pharmaceutical products. For the life science field, there is a great advantage in using neutron and photon technologies to solve difficult problems. From the structures of isolated protein complexes to the molecular dynamics of whole cells, neutron methods can achieve a resolution in complex systems that is inaccessible to other techniques. Biology is fortunate to be rich in water and hydrogen, and these advanced techniques help exploit the differential sensitivity of neutrons to this element and its main isotope, deuterium. Moreover, neutrons have wave properties that allow them to be used in the life sciences in a similar way to light, X-rays and electrons.
